Public health is having a moment. Public health professionals are advising policy makers and are frequently featured in the media. Public trust in public health is high. COVID-19, however, has also exposed the depth and deadliness of a core public health issue: structural and systemic racism. This moment offers the potential not just for more investment in public health—which is desperately needed—but to shift the paradigm beyond the current essential functions framework, to a more strategic role to comprehensively and effectively address social determinants of health and improve health equity. How can public health rise to this challenge?